Erin Lavik, Sc.D. Elmer Lincoln Lindseth Associate Professor in Biomedical Engineering Office: Room 111 Wickenden Building Phone: 216-368-0400 Fax: (216) 368-4969 Email: erin.lavik@case.edu Mail Address: Room 309 Wickenden Building 2071 Martin Luther King Jr. Drive Cleveland, OH 44106-7207

Selected links:

• Department of Biomedical Engineering

• Lab website : www.laviklab.org

Research Summary

We are working to develop translatable approaches to treat injuries to and diseases of the central nervous system including spinal cord injury, glaucoma, and retinal degeneration. Our tools involve polymer science, drug delivery, and cellular therapy approaches.

Recent Publications

Bertram, J., Williams, C., Robinson, R., Segal, S. S., Flynn, N. T. and Lavik, E., Intravenous Hemostat: Nanotechnology to Halt Bleeding. Science Translational Medicine,  1(11). 2009.

Rauch, M. F., Hynes, S. R., Bertram, J., Redmond, A., Robinson, R., Williams, C., Xu, H., Madri, J. A. and Lavik, E. B., Engineering angiogenesis following spinal cord injury: A coculture of neural progenitor and endothelial cells in a degradable polymer implant leads to an increase in vessel density and formation of the blood-spinal cord barrier. European Journal of Neuroscience,  29(1): p. 132-145. 2009.

Bertram, J.*, Saluja, S. S.*, McKain, J. A. and Lavik, E. B., Sustained Delivery of Timolol Maleate from Poly(lactic-co-glycolic acid)/Poly(lactic acid) Microspheres for over 3 months. Journal of Microencapsulation,  26(1): p. 18-26. 2009. *contributed equally

Hynes, S. R., Rauch, M. F., Bertram, J. and Lavik, E. B. A library of tunable poly(ethylene glycol)/poly-L-lysine hydrogels to investigate the materials cues that influence neural stem cell differentiation. Journal of Biomedical Materials Research Part A, epub 2008.

Rauch, M. F., Michaud, M., Xu, H., Madri, J. A. and Lavik, E. B., Coculture of  primary neural progenitor and endothelial cells in a synthetic, degradable macroporous gel promotes stable vascular networks in vivo. Journal of Biomaterials Science-Polymer Edition,  19(11): p. 1469-1485. 2008.

Hynes, S. R., McGregor, L. and Lavik, E. B. Photopolymerizable hydrogels for neural tissue engineering. Journal of Biomedical Materials Science: Polymer Edition 18: 1017-1030, 2007.